Series: Methods in Molecular Biology (Book 228)
Hardcover: 334 pages
Publisher: Humana Press; 2003 edition (May 29, 2003)
Product Dimensions: 6.1 x 0.8 x 9.2 inches
Amazon Rank: 5781825
Format: PDF ePub djvu ebook
Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial orientation of amino acids in the active site of an enzyme demonstrates how substrate specificity is defined, and assists the medicinal chemist in the design of s- cific, tight-binding inhibitors. The shape and contour of a protein surface hints at its interaction with other proteins and with its environment...
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